Recruiting

Participating in a clinical trial allows those who have been diagnosed with a serious illness, like mesothelioma, to contribute to medical research. Each clinical trial has unique criteria and guidelines that prospective participants must meet in order to be considered for inclusion in the study. Because there are both benefits and risks to participating in a clinical trial it is always best to discuss any interest you may have with your doctor. Provided below is a list of active mesothelioma clinical trials that are still recruiting and enrolling participants. Click on a link to learn more about each study and the criteria for participation.

• Pemetrexed Disodium and Cisplatin With or Without Cediranib Maleate in Treating Patients With Malignant Pleural Mesothelioma

  Conditions:

  Advanced Malignant Mesothelioma; Epithelioid Mesothelioma; Recurrent Malignant Mesothelioma; Sarcomatoid Mesothelioma

  Last Updated:

  January 29, 2015

  Status:

  Recruiting

• Thromboelastography During Surgery for Malignant Pleural Mesothelioma

  Conditions:

  Coagulopathy; Mesothelioma

  Last Updated:

  January 28, 2015

  Status:

  Recruiting

• Placebo Controlled Study of VS-6063 in Subjects With Malignant Pleural Mesothelioma

  Conditions:

  Malignant Pleural Mesothelioma

  Last Updated:

  January 26, 2015

  Status:

  Recruiting

• Clinical Trial of Intraperitoneal Hyperthermic Chemotherapy

  Conditions:

  Ovarian Cancer; Peritoneal Cancer; Fallopian Tube Cancer; Uterine Cancer; Mesotheliomas; Gastrointestinal Cancers; Cervical Cancer

  Last Updated:

  January 26, 2015

  Status:

  Recruiting

• CAR T Cell Receptor Immunotherapy Targeting Mesothelin for Patients With Metastatic Cancer

  Conditions:

  Metastatic Cancer; Pancreatic Cancer; Mesothelioma; Ovarian

  Last Updated:

  January 23, 2015

  Status:

  Recruiting

• A Study of LY3023414 in Participants With Advanced Cancer

  Conditions:

  Advanced Cancer; Metastatic Cancer; Non-Hodgkin's Lymphoma; Metastatic Breast Cancer; Malignant Mesothelioma; Non-small Cell Lung Cancer

  Last Updated:

  January 22, 2015

  Status:

  Recruiting

• MPM PDT Phase II Trial

  Conditions:

  Epitheliod Malignant Pleural Mesothelioma

  Last Updated:

  January 21, 2015

  Status:

  Recruiting

• Study Using Chemotherapy +/- Pleurectomy/Decortication Followed By Intensity Modulated Radiation Therapy

  Conditions:

  Mesothelioma

  Last Updated:

  January 16, 2015

  Status:

  Recruiting

• αDC1 Vaccine + Chemokine Modulatory Regimen (CKM) as Adjuvant Treatment of Peritoneal Surface Malignancies

  Conditions:

  Malignant Neoplasm of Pancreas Metastatic to Peritoneal Surface; Malignant Peritoneal Mesothelioma; Peritoneal Carcinomatosis

  Last Updated:

  January 16, 2015

  Status:

  Recruiting

• Mithramycin for Lung, Esophagus, and Other Chest Cancers

  Conditions:

  Lung Cancer; Esophageal Cancer; Mesothelioma; Gastrointestinal Neoplasms; Breast Cancer

  Last Updated:

  January 15, 2015

  Status:

  Recruiting

• SS1P and Pentostatin Plus Cyclophosphamide for Mesothelioma

  Conditions:

  Mesothelioma

  Last Updated:

  January 14, 2015

  Status:

  Recruiting

• Safety and Efficacy of Listeria in Combination With Chemotherapy as Front-line Treatment for Malignant Pleural Mesothelioma

  Conditions:

  Malignant Pleural Mesothelioma

  Last Updated:

  January 12, 2015

  Status:

  Recruiting

• Cancer Research Repository for Individuals With Cancer Diagnosis and High Risk Individuals.

  Conditions:

  Pancreatic Cancer; Thyroid Cancer; Lung Cancer; Esophageal Cancer; Thymus Cancer; Colon Cancer; Rectal Cancer; GIST; Anal Cancer; Bile Duct Cancer; Duodenal Cancer; Gallbladder Cancer; Gastric Cancer; Liver Cancer; Small Intestine Cancer; Peritoneal Surface Malignancies; Familial Adenomatous Polyposis; Lynch Syndrome; Bladder Cancer; Kidney Cancer; Penile Cancer; Prostate Cancer; Testicular Cancer; Ureter Cancer; Urethral Cancer; Hypopharyngeal Cancer; Laryngeal Cancer; Lip Cancer; Oral Cavity Cancer; Nasopharyngeal Cancer; Oropharyngeal Cancer; Paranasal Sinus Cancer; Nasal Cavity Cancer; Salivary Gland Cancer; Skin Cancer; CNS Tumor; CNS Cancer; Mesothelioma

  Last Updated:

  December 12, 2014

  Status:

  Recruiting

• Intrapleural Administration of HSV1716 to Treat Patients With Malignant Pleural Mesothelioma.

  Conditions:

  Malignant Pleural Mesothelioma

  Last Updated:

  December 8, 2014

  Status:

  Recruiting

• A Study of Cetuximab Combined With Cisplatin or Carboplatin/Pemetrexed as First Line Treatment in Patients With Malignant Pleural Mesothelioma.

  Conditions:

  Cancer

  Last Updated:

  December 4, 2014

  Status:

  Recruiting

• Register With Patients in Which Hyperthermic Intra-Peritoneal Chemotherapy (HIPEC) Was Performed

  Conditions:

  Peritoneal Carcinomatosis; Pseudomyxoma Peritonei; Peritoneal Mesothelioma

  Last Updated:

  December 3, 2014

  Status:

  Recruiting

• Phase II Study of Adjuvant WT-1 Analog Peptide Vaccine in MPM Patients After MSK10-134

  Conditions:

  Malignant Pleural Mesothelioma

  Last Updated:

  December 2, 2014

  Status:

  Recruiting

• Combination of Gemcitabine and Imatinib Mesylate in Pemetrexed-pretreated Patients With Pleural Mesothelioma

  Conditions:

  Mesothelioma, Malignant

  Last Updated:

  November 28, 2014

  Status:

  Recruiting

• Pharmacogenetics Of Vinorelbine In Malignant Pleural Mesothelioma Patients

  Conditions:

  Malignant Pleural Mesothelioma

  Last Updated:

  November 19, 2014

  Status:

  Recruiting

• Study of the Combination of Tivantinib Plus Pemetrexed and Carboplatin

  Conditions:

  Malignant Pleural Mesothelioma; Nonsquamous Nonsmall Cell Neoplasm of Lung

  Last Updated:

  November 19, 2014

  Status:

  Recruiting

• Study of the Glutaminase Inhibitor CB-839 in Solid Tumors

  Conditions:

  Solid Tumors; Triple-Negative Breast Cancer; Non Small Cell Lung Cancer; Renal Cell Carcinoma; Mesothelioma; Fumarate Hydratase (FH)-Deficient Tumors; Succinate Dehydrogenase (SDH)-Deficient Gastrointestinal Stromal Tumors (GIST); Succinate Dehydrogenase (SDH)-Deficient Non-gastrointestinal Stromal Tumors; Tumors Harboring Isocitrate Dehydrogenase-1 (IDH1) and IDH2 Mutations

  Last Updated:

  November 13, 2014

  Status:

  Recruiting

• Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining

  Conditions:

  Pulmonary Metastases From Cancers; Mediastinal or Chest Wall Neoplasms; Malignant Pleural Mesotheliomas NOS; Esophageal Cancers NOS; Lung Cancer NOS

  Last Updated:

  November 11, 2014

  Status:

  Recruiting

• Window of Opportunity Study of VS-6063 (Defactinib) in Participants With Surgical Resectable Malignant Pleural Mesothelioma.

  Conditions:

  Malignant Pleural Mesothelioma

  Last Updated:

  October 27, 2014

  Status:

  Recruiting

• Re-directed T Cells for the Treatment (FAP)-Positive Malignant Pleural Mesothelioma

  Conditions:

  Malignant Pleural Mesothelioma

  Last Updated:

  October 27, 2014

  Status:

  Recruiting

• A Dose Escalation Study to Assess Safety of GSK2256098 (FAK Inhibitor) in Combination With Trametinib (MEK Inhibitor) in Subjects With Advanced Solid Tumors

  Conditions:

  Cancer

  Last Updated:

  October 27, 2014

  Status:

  Recruiting

• Peritoneal Surface Malignancies - Characterization, Models and Treatment Strategies

  Conditions:

  Pseudomyxoma Peritonei.; Colorectal Carcinoma.; Ovarian Carcinoma.; Mesothelioma.

  Last Updated:

  October 22, 2014

  Status:

  Recruiting

• Adjuvant Tumor Lysate Vaccine and Iscomatrix With or Without Metronomic Oral Cyclophosphamide and Celecoxib in Patients With Malignancies Involving Lungs, Esophagus, Pleura, or Mediastinum

  Conditions:

  Lung Cancer; Esophageal Cancer; Malignant Pleural Mesothelioma; Sarcoma; Thymic Carcinoma

  Last Updated:

  October 21, 2014

  Status:

  Recruiting

• LEE011 for Patients With CDK4/6 Pathway Activated Tumors (SIGNATURE)

  Conditions:

  Tumors With CDK4/6 Pathway Activation

  Last Updated:

  October 19, 2014

  Status:

  Recruiting

• Effect of Fas Ligand Polymorphism on Patients With Platinum/Gemcitabine-Treated Malignant Pleural Mesothelioma

  Conditions:

  Malignant Pleural Mesothelioma

  Last Updated:

  October 18, 2014

  Status:

  Recruiting

• Erlotinib Hydrochloride in Treating Patients With Malignant Peritoneal Mesothelioma

  Conditions:

  Malignant Peritoneal Mesothelioma

  Last Updated:

  October 14, 2014

  Status:

  Recruiting

• Tissue Procurement for Gastric Cancer, Gastrointestinal Stromal Tumors (GIST), Esophageal Cancer, Pancreas Cancer, Hepatocellular Cancer, Biliary Cancer, Neuroendocrine, Peritoneal Mesothelioma, Anal Cancer and Colorectal Cancer in Patients Undergoing Surgery or Biopsy

  Conditions:

  Gastric Cancers

  Last Updated:

  October 14, 2014

  Status:

  Recruiting

• Intra-pleural Administration of GL-ONC1, a Genetically Modified Vaccinia Virus, in Patients With Malignant Pleural Effusion: Primary, Metastases and Mesothelioma

  Conditions:

  Lung Cancer

  Last Updated:

  October 7, 2014

  Status:

  Recruiting

• Ph 1 Study in Subjects With Tumors Requiring Arginine to Assess ADI-PEG 20 With Pemetrexed and Cisplatin

  Conditions:

  Pleural Mesothelioma Malignant Advanced; Peritoneal Mesothelioma Malignant Advanced; Non-squamous Non-small Cell Lung Carcinoma Stage IIIB/IV (NSCLC)

  Last Updated:

  September 21, 2014

  Status:

  Recruiting

• Proton Beam Radiation Therapy in Treating Patients With Recurrent Thoracic Cancer Who Have Received Prior Radiation Therapy

  Conditions:

  Lung Metastases; Recurrent Malignant Mesothelioma; Recurrent Non-small Cell Lung Cancer; Recurrent Small Cell Lung Cancer; Recurrent Thymoma and Thymic Carcinoma

  Last Updated:

  September 17, 2014

  Status:

  Recruiting

• Intrapleural Measles Virus Therapy in Patients With Malignant Pleural Mesothelioma

  Conditions:

  Recurrent Malignant Mesothelioma; Stage IA Malignant Mesothelioma; Stage IB Malignant Mesothelioma; Stage II Malignant Mesothelioma; Stage III Malignant Mesothelioma; Stage IV Malignant Mesothelioma

  Last Updated:

  September 12, 2014

  Status:

  Recruiting

• Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer Receiving Radiation Therapy to the Thorax With or Without Chemotherapy

  Conditions:

  Lymphoma; Malignant Mesothelioma; Malignant Pericardial Effusion; Malignant Pleural Effusion; Non-small Cell Lung Cancer; Small Cell Lung Cancer; Soft Tissue Sarcoma; Thymoma and Thymic Carcinoma

  Last Updated:

  September 12, 2014

  Status:

  Recruiting

• Photodynamic Therapy During Surgery in Treating Patients With Pleural Malignancy

  Conditions:

  Stage III Malignant Mesothelioma; Stage IIIB Non-small Cell Lung Cancer; Stage IV Malignant Mesothelioma; Stage IV Non-small Cell Lung Cancer

  Last Updated:

  September 5, 2014

  Status:

  Recruiting

• Ganetespib With Platinum, in Patients With Malignant Pleural Mesothelioma

  Conditions:

  Lung Cancer - Malignant Pleural Mesothelioma

  Last Updated:

  September 3, 2014

  Status:

  Recruiting

• Clinical and Histopathologic Characteristics of BAP1 Mutations

  Conditions:

  Malignant Pleural Mesothelioma (MPM); Choroidal Nevus; Primary Uveal Melanoma (UM); Metastatic Uveal Melanoma (UM); Renal Cell Carcinoma; Cholangiocarcinoma

  Last Updated:

  August 29, 2014

  Status:

  Recruiting

• Pilot Study of Bisphosphonate Therapy (Zoledronic Acid) in Patients With Malignant Mesothelioma (UAB 0901)

  Conditions:

  Mesothelioma

  Last Updated:

  August 26, 2014

  Status:

  Recruiting

• Randomized Study of Adjuvant WT-1 Analog Peptide Vaccine in Patients With Malignant Pleural Mesothelioma (MPM) After Completion of Combined Modality Therapy

  Conditions:

  Malignant Pleural Mesothelioma

  Last Updated:

  August 18, 2014

  Status:

  Recruiting

• Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma

  Conditions:

  Mesothelioma

  Last Updated:

  July 19, 2014

  Status:

  Recruiting

• ATREUS - Phase II Study on the Activity of Trabectedin in Patients With Malignant Pleural Mesothelioma (MPM)

  Conditions:

  Malignant Pleural Mesothelioma

  Last Updated:

  July 16, 2014

  Status:

  Recruiting

• Do Your Genes Put You at a Higher Risk of Developing Mesothelioma

  Conditions:

  Mesothelioma

  Last Updated:

  July 9, 2014

  Status:

  Recruiting

• Early Palliative Care With Standard Oncology Care Versus Standard Oncology Care Alone in Advanced Lung and Non-colorectal Gastrointestinal Malignancies

  Conditions:

  Non-small Cell Lung Cancer; Small Cell Lung Cancer; Mesothelioma; Esophageal Cancer; Gastric Cancer; Liver Cancer; Pancreatic Cancer

  Last Updated:

  July 3, 2014

  Status:

  Recruiting

• Tumor Cell Vaccines With ISCOMATRIX Adjuvant and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers and Malignant Pleural Mesotheliomas

  Conditions:

  Mesolthelioma; Esophageal Cancer; Lung Cancer; Thoracic Sarcomas

  Last Updated:

  June 26, 2014

  Status:

  Recruiting

• Short Neoadjuvant Hemithoracic IMRT for MPM

  Conditions:

  Malignant Pleural Mesothelioma

  Last Updated:

  June 24, 2014

  Status:

  Recruiting

• PIT: Prophylactic Irradiation of Tracts in Patients With Malignant Pleural Mesothelioma

  Conditions:

  Mesothelioma

  Last Updated:

  June 11, 2014

  Status:

  Recruiting

• CART-meso in Mesothelin Expressing Cancers

  Conditions:

  Metastatic Pancreatic (Ductal) Adenocarcinoma; Epithelial Ovarian Cancer; Malignant Epithelial Pleural Mesothelioma

  Last Updated:

  June 9, 2014

  Status:

  Recruiting

• Pilot Study of Allogeneic Tumor Cell Vaccine With Metronomic Oral Cyclophosphamide and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers, Thymic Neoplasms, and Malignant Pleural Mesotheliomas

  Conditions:

  Lung Cancer; Esophageal Cancer; Malignant Pleural Mesothelioma; Sarcoma; Thymic Carcinoma

  Last Updated:

  May 3, 2014

  Status:

  Recruiting

• Validation of the MiCK Assay

  Conditions:

  Mesothelioma, Small Cell Lung Cancer, NSCLC

  Last Updated:

  April 18, 2014

  Status:

  Recruiting

• Two-Part, Open-Label, Multi-Center, Phase 1/2 Study of BIW-8962 as Monotherapy in Subjects With Lung Cancer

  Conditions:

  Phase 1 Portion : Non Small Cell Lung Cancer(NSCLC), Small Cell Lung Cancer(SCLC), Mesothelioma; Phase 2 Portion : Small Cell Lung Cancer(SCLC)

  Last Updated:

  January 28, 2014

  Status:

  Recruiting

• Phase II Study of Six Hours Low Dose Gemcitabine Plus Cisplatin in the Treatment for Advanced Pleural Mesothelioma

  Conditions:

  Advanced Malignant Pleural Mesothelioma

  Last Updated:

  January 15, 2014

  Status:

  Recruiting

• Intrapleural AdV-tk Therapy in Patients With Malignant Pleural Effusion

  Conditions:

  Malignant Pleural Effusion; Lung Cancer; Mesothelioma; Breast Cancer; Ovarian Cancer

  Last Updated:

  November 22, 2013

  Status:

  Recruiting

• Intracavitary Cisplatin-Fibrin Localized Chemotherapy After Pleurectomy/Decortication for Malignant Pleural Mesothelioma

  Conditions:

  Malignant Pleural Mesothelioma

  Last Updated:

  April 4, 2013

  Status:

  Recruiting

• A Phase II Trial to Assess TroVax® Plus Chemotherapy in Patients With Malignant Pleural Mesothelioma

  Conditions:

  Malignant; Pleural; Mesothelioma

  Last Updated:

  March 11, 2013

  Status:

  Recruiting

• Pemetrexed Disodium or Observation in Treating Patients With Malignant Pleural Mesothelioma Without Progressive Disease After First-Line Chemotherapy

  Conditions:

  Malignant Mesothelioma

  Last Updated:

  February 8, 2013

  Status:

  Recruiting

• Phase II Study of NGR-hTNF Versus Placebo as Maintenance Treatment in Patients With Advanced Malignant Pleural Mesothelioma

  Conditions:

  Advanced Malignant Pleural Mesothelioma

  Last Updated:

  January 28, 2013

  Status:

  Recruiting

• The ISET (Isolation by Size of Epithelial Tumor Cells) and the CellSearch Methods in Malignant Pleural Mesothelioma

  Conditions:

  Pleural Neoplasms; Mesothelioma; Pneumothorax; Parathyroid Neoplasms; Benign Tumor of the Thyroid; Tumor of the Thyroid

  Last Updated:

  January 23, 2013

  Status:

  Recruiting

• Early Detection of Lung Cancer and Mesothelioma in Workers Exposed to Asbestos

  Conditions:

  Mesothelioma; Lung Cancer

  Last Updated:

  October 30, 2012

  Status:

  Recruiting

• Collecting Tumor Samples From Patients With Gynecological Tumors

  Conditions:

  Cancer

  Last Updated:

  August 30, 2012

  Status:

  Recruiting

• The Anti-CTLA-4 Monoclonal Antibody Tremelimumab in Malignant Mesothelioma

  Conditions:

  Malignant Mesothelioma

  Last Updated:

  July 31, 2012

  Status:

  Recruiting

• Early Diagnosis of Lung Cancer and Mesothelioma in Prior Asbestos Workers

  Conditions:

  Lung Cancer; Mesothelioma

  Last Updated:

  January 19, 2012

  Status:

  Recruiting

• Velcade and Eloxatin for Patients With Malignant Pleural or Peritoneal Mesothelioma

  Conditions:

  Mesothelioma

  Last Updated:

  October 28, 2011

  Status:

  Recruiting

• Trimodal Lung-Sparing Treatment of Pleural Mesothelioma

  Conditions:

  Pleural Mesothelioma

  Last Updated:

  October 28, 2011

  Status:

  Recruiting

• N-AcetylCysteine vs. Placebo to Prevent Neurotoxicity Induced by Platinum Containing Chemotherapy

  Conditions:

  Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell Lung; Mesothelioma

  Last Updated:

  August 8, 2011

  Status:

  Recruiting

• Trimodality Therapy for Malignant Pleural Mesothelioma

  Conditions:

  Malignant Pleural Mesothelioma

  Last Updated:

  April 26, 2011

  Status:

  Recruiting

• Cisplatin With Alimta or Gemcitabine in Long Infusion for Mesothelioma

  Conditions:

  Mesothelioma

  Last Updated:

  January 21, 2011

  Status:

  Recruiting

• Intrapleural Gene Transfer for Pleural Mesothelioma

  Conditions:

  Malignant Pleural Mesothelioma

  Last Updated:

  September 29, 2010

  Status:

  Recruiting

• Axitinib in Malignant Mesothelioma

  Conditions:

  Malignant Pleural Mesothelioma

  Last Updated:

  September 28, 2010

  Status:

  Recruiting

• Mesothelin and Osteopontin as Diagnostic Markers in Patients With Mesothelioma or Atypical Mesothelial Hyperplasia

  Conditions:

  Malignant Mesothelioma; Metastatic Cancer

  Last Updated:

  December 13, 2009

  Status:

  Recruiting

• Surgery Plus Intraoperative Peritoneal Hyperthermic Chemotherapy (IPHC) to Treat Peritoneal Carcinomatosis

  Conditions:

  Stomach Neoplasms; Colorectal Neoplasms; Neoplasm Metastasis; Mesothelioma

  Last Updated:

  February 12, 2009

  Status:

  Recruiting

• An Efficacy Study of Milataxel (TL139) Administered Orally for Malignant Mesothelioma

  Conditions:

  Mesothelioma

  Last Updated:

  May 22, 2008

  Status:

  Recruiting